BRAIN TUMORSANEURYSMSVASCULAR MALFORMATIONSTRIGEMINAL NEURALGIASPINE NECK BACKPARKINSONS DISEASEHEMIFACIAL SPASMCARPAL TUNNEL SYNDROME

Choroid Plexus Papilloma (CPP): Overview

 

  • Together with Teratoma, PNET, and High Grade Glioma is one of the most common brain tumors before age of two years.

  • It comprises less than 1% of brain tumors.

  • These are typically located in the lateral ventricle (50%), or in the fourth ventricle (40% and more commonly in adults), in the third ventricle (10%), and rarely in the cerebellopontine angle (CPA).  They are rarely bilateral (4%).

  • They are typically well circumscribed, vascular, and contrast enhancing.

  • Patients typically present with hydrocephalus as a result of increased cerebrospinal fluid (CSF) production, or due to blockage of CSF flow from direct obstruction of hemorrhage.

  • Surgical resection usually has a good outcome with rare recurrences.

  • There are rare malignant transformations.

  • As with intraventricular meningiomas, they are more frequently on the left intraventricular space.

  • This tumor needs to be differentiated from choroid plexus carcinoma (CPC) which has 15% incidence of CPPs.  CPCs usually invade the parenchyma of brain and seed the CSF.  Treatment of CPC is with surgery and radiation with or without chemotherapy with poor prognosis.